Phospholipase a2 receptor antibody pla2r

WebMar 14, 2024 · The discovery of antibodies against M-type phospholipase A2 receptor (PLA2R) situated on the cell surface of human podocytes has been a turning point for the … WebAnti-phospholipase A2 receptor (PLA2R) antibodies are highly specific for the diagnosis of primary membranous nephropathy. If a patient is already known to have anti …

THSD7 - Overview: Thrombospondin Type-1 Domain-Containing 7A Antibodies …

WebPhospholipases A 2 include several unrelated protein families with common enzymatic activity. Two most notable families are secreted and cytosolic phospholipases A 2. Other families include Ca 2+ independent PLA2 (iPLA2) and lipoprotein-associated PLA2s (lp-PLA2), also known as platelet activating factor acetylhydrolase (PAF-AH). list of books in catholic bible https://families4ever.org

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WebAug 19, 2014 · Background The presence of antibodies against the M-type phospholipase A2 receptor (PLA2R-AB) is considered to be a promising serological diagnostic biomarker of idiopathic membranous nephropathy (iMN). However, controversy remains about the diagnostic accuracy of serum PLA2R-AB testing. Here, we performed a comprehensive … WebOct 8, 2015 · PLA2R — Phospholipase A2 Receptor Antibodies, Serum View all test information details. 63036 — Phospholipase A2 Receptor (PLA2R) Immunofluorescent … WebIn 2009, Beck et al 2 first discovered that the extracellular domain of phospholipase A2 receptor (PLA2R) was used as the mutant antigen to activate autoimmunity response. Combined with the PLA2R antibodies produced in the body, PLA2R forms the insitus immune complex, resulting in the injury of basement membrane, which was the major … list of books in order by author

Anti-Phospholipase A2 Receptor - Anti-PLA2R

Category:Ultrasensitive Quantitation of Anti-Phospholipase A2 Receptor Antibody …

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Phospholipase a2 receptor antibody pla2r

JCM Free Full-Text Membranous Nephropathy: From Research …

WebFeb 1, 2024 · The reporting of anti-phospholipase A2 receptor antibody (PLA2RAb) positivity in 70% of patients with primary MN (PMN) in 2009 was a significant advance in the understanding of the disease pathogenicity. What is the antigen? The M-type phospholipase A2 receptor (PLA2R) on the cell surface of podocytes is the target antigen for PLA2RAb. WebAnti-PLA2R antibody [CL0474] (ab188028) Datasheet SDS Submit a review Submit a question References (2) Key features and details Mouse monoclonal [CL0474] to PLA2R Suitable for: IHC-P, WB, ICC Reacts with: Human Isotype: IgG1 You may also be interested in Primary Anti-Ext1 antibody (ab126305) Peptide PLA2R peptide (ab176432)

Phospholipase a2 receptor antibody pla2r

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WebObjective To explore the value of anti-phospholipase A2 receptor (PLA2R) antibody in the diagnosis and disease activity monitoring of idiopathic membranous nephropathy (IMN).Methods A total of 233 patients with IMN proven by kidney biopsy at Peking Union Medical College Hospital from January 2012 to March 2014 were enrolled in this study ... WebAnti-phospholipase A2 receptor (PLA2R) antibodies are highly specific for the diagnosis of primary membranous nephropathy. As many as 70% to 75% of patients with primary membranous nephropathy are positive for anti-PLA2R. This test can be used to identify …

Web开馆时间：周一至周日7:00-22:30 周五 7:00-12:00; 我的图书馆 WebPhospholipase A2 receptor (PLA2R) is present in normal podocytes and in immune deposits in patients with idiopathic membranous nephropathy, indicating that it is a major antigen …

WebThrombospondin Type-1 Domain-Containing 7A Antibodies, Serum Specimen Fees & Codes Setup & Updates Useful For Distinguishing primary from secondary membranous nephropathy cases with antibodies against THSD7A Method Name Indirect Immunofluorescence Assay (IFA) NY State Available Yes Reporting Name THSD7A Ab, S … WebDec 2, 2024 · Objective To investigate the correlation of M-type phospholipase A2 receptor (PLA2R) expression and serum anti-PLA2R antibody with the clinical parameters and …

WebPhospholipase A2 Receptor (PLA2R) Antibody, IgG with Reflex to Titer 2011828 Copy Utility Click to copy Test Number / Name Choose the Right Test ARUP Consult® assists with …

WebAnti-phospholipase A2 receptor antibody (anti-PLA2R) has emerged as a reliable biomarker for diagnosis, monitoring of disease activity and response to therapy in primary MN. … list of books i have purchased for my kindleWebJul 15, 2024 · (a) PM2.5 induces extrarenal anti-PLA2R antibody production. Inhalation of PM2.5 results in the accumulation and activation of alveoli macrophages and neutrophils. PLA2R that is presented on these cells can be discharged into the inflammatory space, when neutrophil extracellular traps (NETs) and macrophage extracellular traps (METs) are … list of books in the 1611 kjv bibleWebJun 15, 2024 · Materials and methods: An open-label prospective comparative study included 56 PMN patients (pts) with nephrotic syndrome (NS) and high serum level of antibodies to the phospholipase A2 receptor anti-PLA2R (mean age 5112 years, men 70%). We recorded demographic and clinical parameters at the time of kidney biopsy, data from … images of sluggoWebbeck等 首次在成人imn患者血清中检测到抗m型磷脂酶a2受体(pla2r)的自身抗体，并发现抗体滴度与患者蛋白尿的消长相关，提示pla2r可能是imn的重要靶抗原。我们前期已针对血清pla2r抗体进行检测，发现病情缓解的imn患者血清学阳性率明显降低，提示单纯采用血 … images of smacking headWebJun 29, 2016 · The phospholipase A2 receptor (PLA2R) is the major target antigen (Ag) in idiopathic membranous nephropathy (IMN). Recently, several types of immunoassay … images of small animal tracks in the snowWebDec 15, 2024 · The discovery of the phospholipase A2 receptor (PLA2R) antibody in 2009 has induced a paradigm shift in both the diagnosis and monitoring of patients. Two serological tests are routinely used: the enzyme-linked immunosorbent assay (ELISA), which is quantitative, and the immunofluorescence assay (IFA), which is more sensitive. list of books in outlander seriesWebThe discovery in 2009 of the M-type phospholipase A2 receptor (PLA2R) as the primary target in membranous nephropathy (MN) greatly advanced basic and clinical research. … images of sly stallone