Pdgfra-creer
SpletBy using this site, you agree to our Terms and Conditions Got it! Splet08. okt. 2008 · By in situ hybridization, the authors found that Pdgfra mRNA was detected in nearly all cre mRNA–expressing cells in both gray and white matter. A tradeoff with inducible control is that the...
Pdgfra-creer
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Splet02. feb. 2024 · We developed a dual-recombinase intersectional targeting approach by using Pdgfra-DreER, Pdgfrb-CreER, and a Cre/Dre double-dependent reporter Ai66 to mark … Splet28. avg. 2016 · To confirm specificity of PDGFRa-CreER and exclude the possibility of non-specific Cre activation with CTX injury, we compared tamoxifen and vehicle-treated PDGFRa-CreER mice harbouring the mT/mG loxP flanked conditional reporter. In these studies, GFP+ cells, indicative of Cre-mediated recombination, were observed only in …
Splet27. jul. 2024 · As a proof of principle that the PDGFRβ - P2A - CreER T2 mouse line is an efficient tool to drive genetic modifications in perivascular cells, we used it to specifically remove Notch signaling in this population. Notch signaling plays an important role in mural cells, which primarily express the Notch3 receptor [ 1 ]. Splet16. avg. 2024 · Platelet-derived growth factor (PDGF) promotes tissue repair and fibrosis, but the relationship between PDGF and myofibroblasts is unclear. Using mice with lineage tracing linked to PDGF receptor α (PDGFRα) gene mutations, we examine cell fates during skin wound healing.
SpletAdditionally, Pdgfra-CreER T2 mice unexpectedly express the transgene in a small number of neurons in the piriform cortex (Clarke et al., 2012). This unwanted or unexpected transgene expression ... Splet10. apr. 2024 · For Pdgfra DreER-tdTomato, Col1a2 CreER Tnc fl/fl and Tnc fl/fl mice, tamoxifen was administered at 5-week-old for 5 consecutive days, and psoriasis mouse model was performed after 2-week washout ...
SpletA survey by double in situ hybridization demonstrated that Pdgfra and Cre mRNA was in the same cells in striatum (e), neocortex (g, h), CC, hippocampus (Hip) and anterior piriform …
SpletIt can be classified into cells positive for vascular endothelial growth factor receptor 2 (VEGFR2 or FLK1) or platelet-derived growth factor receptor α (PDGFRα), representing lateral and paraxial mesoderm, respectively. Era and colleagues generated knock-in mice carrying GFP-Cre-ERT2 at the start codon of Pdgfra [1]. They confirmed Cre ... does grant money have to be paid backSpletPdgfra-creERTM transgenic mice can be used to create conditional mutations in oligodendrocyte precursor or NG2 + cells in the adult forebrain and spinal cord. They may … f7600cSplet14. sep. 2016 · We report that Pdgfrα-CreER T2 transgenic mice are highly suitable for OPC-directed gene recombination in the CNS, can be used to achieve robust recombination in … does grant wahl have any childrendoes grant have to be paid backSplet07. feb. 2024 · Clinical resource with information about PDGFRA, A genome-wide association study for corneal curvature identifies the platelet-derived growth factor … f75 wc 7SpletPlatelet-derived growth factor (PDGF) and its receptor play an important role in embryogenesis. PDGF receptor α (PDGFRα) is expressed specifically in the embryonic … does grant wahl have childrenSplet013148 - PDGFRa-CRE Strain Details. Technical Information Scientists. Overview. f7600t