Mycothiol synthase
Web9 nov. 2007 · In this report, we have established that it is MSH and in extension mycothiol-dependent enzymes play a role in detoxification of electrophiles, alkylating agents, oxidants, and antibiotics. MSH and MSH-dependent enzymes also play a role in protection against acid stress but not osmotic stress. WebUniProtKB. x; UniProtKB. Protein knowledgebase. UniParc. Sequence archive. Help. Help pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects.
Mycothiol synthase
Did you know?
WebThis enzyme catalyses the last step in the biosynthesis of mycothiol, the major thiol in most actinomycetes, including Mycobacterium . The enzyme is a member of a large family of … Web21 apr. 2006 · In mycobacteria, mycothiol (MSH) serves as the major systemic protectant. MSH (1 d - myo -inosityl 2- ( N -acetyl- l -cysteinyl) amido-2-deoxy-α- d -glucopyranoside), is the dominant low molecular-weight thiol, reducing agent, and storage form of cysteine, produced by mycobacteria and a number of other actinomycetes [ 10].
Webmycothiol synthase. Gene provides a unified query environment for genes defined by sequence and/or in NCBI's Map Viewer. mshD mycothiol synthase [] Gene ID: 15147133, updated on 14-Dec-2024. Summary. Other designations. mycothiol synthase ... Web2 feb. 2016 · Aminoacyl-tRNA syntheases (AARSs) carry out two important functions in translation of the Genetic Information [ 1, 2]: Chemical Activation and Information Transfer. The Chemical Activation function involves a reaction between a carboxyl group of an amino acid (AA) and ATP, affording an aminoacyl~adenylate (Reaction I ): (I)
Webmycothiol synthase. Reaction catalysed 1D-myo-inositol 2- (L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside + acetyl-CoA <=> CoA + H (+) + mycothiol Comment (s) This … WebMycothiol synthase is an enzyme with systematic name acetyl-CoA:desacetylmycothiol O-acetyltransferase. This enzyme catalyses the following chemical reaction This enzyme …
Web21 apr. 2006 · The effect of exogenous oxidative stress on mycothiol (MSH) levels and redox balance was investigated in mycobacteria. Both the thiol-specific oxidant diamide …
WebTIGR03450 (PSSM ID: 132491): Conserved Protein Domain Family mycothiol_INO1, This enzyme, inositol 1-phosphate synthase as found in Actinobacteria, produces an essential precursor for several different products, including mycothiol, which is a glutathione analog, and phosphatidylinositol, which is a phospholipid isley brothers its your thing chordsWeb28 mrt. 2024 · M. tuberculosis (Mtb) produces mycothiol (MSH) in place of glutathione as the most abundant low molecular weight thiol. MSH and associated enzymes (e.g. mycothiol-S-transferase, MST) are thought to play pivotal roles in cellular… Expand discovery.ucl.ac.uk Save to LibrarySave Create AlertAlert Cite Share This Paper kg thicket\\u0027sWeb26 sep. 2005 · The structure of the ternary complex of mycothiol synthase from Mycobacterium tuberculosis with bound desacetylmycothiol and CoA was … isley brothers i got work to doWebmycothiol synthase. Gene provides a unified query environment for genes defined by sequence and/or in NCBI's Map Viewer. mshD mycothiol synthase [] Gene ID: … kg they\u0027veWebMycothiol (MSH or AcCys-GlcN-Ins) is an unusual thiol compound found in the Actinobacteria. It is composed of a cysteine residue with an acetylated amino group … kg this is not goodbye font downloadWeb10 mei 2002 · Mycothiol is a novel thiol produced only by actinomycetes and is the major low molecular weight thiol in mycobacteria. The mycothiol biosynthetic pathway has been postulated to involve ATP-dependent ligation of l -cysteine (Cys) with 1 d - myo -inosityl 2-amino-2-deoxy-α- d -glucopyranoside; GlcN-Ins) catalyzed by MshC to produce Cys … kg thicket\u0027sWebMycothiol (MSH) is an intracellular reducing agent used by mycobacteria (e.g., Mycobacterium tuberculosis) to protect against oxidative damage, a role similar to that … kgt international